Table 3.
Changes 3D from baseline in the 3 DVD tool at 12 months of treatment with OXY-TDS (naive/nonnaive patients).
| 3 DVD | Naive (n=15) mean (SD) |
Nonnaive (n=32) mean (SD) |
Diff (95% CI) | p value |
|---|---|---|---|---|
| DUF (episodes/day)∗ | 7.07 (1.8) | 6.9 (1.5) | 0.4 (−0.7; 1.3) | 0.341 |
| NUF (episodes/night)∗ | 0.87 (0.7) | 0.7 (0.8) | 0.0 (−3.0; 0.7) | 0.411 |
| UF/24 hours (episodes/day)∗ | 8.0 (2.1) | 7.6 (1.7) | 6.3 (−0.4; 1.7) | 0.298 |
| Maximum UV (ml)∗ | 444.6 (486.1) | 302.1 (83.1) | 24.1 (−41.7; 100.0) | 0.461 |
| Nocturnal UV (ml) | 112.6 (84.9) | 143.83 (168.9) | −31.2 (−135.9; 73.5) | 0.550 |
| Mean UV (ml) | 205.5 (54.9) | 191.0 (NA) | 14.5 (−180.6; 209.6) | 0.828 |
| Urgency (episodes/day) | 1.5 (2.1) | 1.5 (1.2) | 0.5 (−0.9; 1.0) | 0.892 |
| Urgency grade∗ | 1.8 (1.3) | 2.5 (1.3) | −0.7 (−1.3; 0.0) | 0.071 |
| UUI (episodes/day)∗ | 0.2 (0.5) | 0.6 (1.0) | 0.0 (−0.3; 0.0) | 0.328 |
| SUI (episodes/day)∗ | 0.0 (0.0) | 0.2 (0.6) | 0.0 (0.0; 0.0) | 0.110 |
| Pad/underwear changes (number/day)∗ | 0.6 (1.0) | 0.8 (1.1) | 0.0 (−0.6; 0.0) | 0.044 |
| Liquid intake/24 h (ml) | 1484.73 (613.5) | 1439.0 (481.9) | 45.7 (−326.4; 417.1) | 0.805 |
| Urine output/24 h (ml) | 1609.17 (446.6) | 1457.89 (347.2) | 151.3 (−115.5; 418.0) | 0.258 |
| Nocturnal urine output (ml) | 167.77 (138.3) | 185.26 (228.2) | −17.5 (−162.6; 127.6) | 0.808 |
3 DVD: 3-day voiding diary; DUF: daytime urinary frequency; NUF: night-time urinary frequency; SD: standard deviation; SUI: stress urinary incontinence; UF/24 h: 24-hour urinary frequency (total number of episodes/24 hours); UUI: urge urinary incontinence. p values: Student's t-test or ∗Wilcoxon signed rank test. Change: mean difference, or ∗Hodges-Lehman estimator of location shift.