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Acquired SMARCB1 Alterations in 200 Sporadic Rhabdoid Tumors
| Allele 1 Alteration |
Allele 2 Alteration | Total | |||
|---|---|---|---|---|---|
| Mutation | Partial Gene Deletion / Duplication |
Whole Gene Deletion |
CN-LOH | ||
| Mutation | 8 (4%) | 1 (0.50%) | 58 (29%) | 27 (13.5%) | 94 (47%) |
| Partial gene deletion / duplication |
— | 5 (2.5%) | 14 (7%) | 11 (5.3%) | 30 (15 %) |
| Whole gene deletion |
— | — | 76 (38%) | — | 76 (38%) |
| Total | 8 (4%) | 6 (3%) | 148 (74%) | 38 (19%) | 200 (100%) |
CN-LOH, copy number neutral loss of heterozygosity.
