Fig. 6. Notch3 expression is associated with GATA-3 in breast cancer clinical cases.
a–d Representative pictures of Notch3 low expression (a), Notch3 high expression (b), GATA-3 low expression (c), and GATA-3 high expression (d). Samples were stained by immunohistochemistry. e Positive correlation between Notch3 and GATA-3 expression (P = 0.0029) analyzed by two-sided t-test. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control. f Proposed model of how Notch3 and GATA-3 regulate EMT in breast cancer