. 2018 Jul 20;32(8):1768–1777. doi: 10.1038/s41375-018-0210-1

Table 2.

Disease response and minimal residual disease status by immunohistochemistry

Parameter	Value (N = 80)
Parameter	Blinded independent central review	Investigator assessment
Durable complete response (primary end point), n (%)^a	24 (30.0)	38 (47.5)
95% confidence interval	20.3, 41.3	36.2, 59.0
Best overall response^a
Complete response, n (%)	33 (41.3)	41 (51.3)
95% confidence interval	30.4, 52.8	39.8, 62.6
Complete response, minimal residual disease negative, n (%)	27 (33.8)	26 (32.5)
95% confidence interval	23.6, 45.2	22.4, 43.9
Partial response, n (%)	27 (33.8)	27 (33.8)
Objective response rate (complete or partial response), n (%)^a	60 (75.0)	63 (78.8)
95% confidence interval	64.1, 84.0	68.2, 87.1

^aTwo-sided confidence interval was calculated using the exact probability method based on the binomial distribution