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Prenatal exposure to DEP impairs arginine-induced insulin secretion (AIIS) in adulthood. The adult offspring were injected ip with arginine (1 mg/g body wt), and plasma glucose (A and B) and insulin (C and D) levels were assessed. Both the response curves (A and C) and the areas under curve (B and D) are presented. nVV = 9, nDV = 7, nVD = 8, and nDD = 11. *P < 0.05, ANOVA.
