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. 2018 Mar 21;315(1):C10–C20. doi: 10.1152/ajpcell.00328.2017

Fig. 1.

Fig. 1.

Evaluation of dextran sulfate sodium (DSS)-colitis in Balb/C mice. A: representative images of excised colons from either control or DSS-colitis cohorts. B: group data of measured colons from either control or colitic mice. Represented data are means ± SE of different groups, collected from 6 different animals in each respective group (*P < 0.001). C: hematoxylin and eosin staining of formalin-fixed colonic tissue. Each image represents a different animal from their corresponding treatment. DSS-colitis (bottom) demonstrates crypt dysplasia, leukocyte infiltration, and thickening of underlying serosa (×20, AxioImager). D: RT-qPCR analysis of multiple cytokines involved in the development of colitis. Asterisks (*) indicate significance of each individual cytokine transcript as compared with control. *P < 0.0001, compared with control; $P < 0.01, compared with control; #P < 0.05, compared with control.