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. 2018 Mar 21;315(1):C10–C20. doi: 10.1152/ajpcell.00328.2017

Fig. 3.

Fig. 3.

Effect of ionomycin on carbachol (CCH)-induced changes in short-circuit current (ISC) from control and acute dextran sulfate sodium (DSS)-colitis mice. A: representative trace of measured ISC following basolateral 100 μM CCH administration to control mucosa. B: representative trace of ISC from DSS-colitis mucosa following basolateral 100 μM CCH administration. C: group data of ΔISC following CCH-administration in control and DSS mice. D: representative trace of ISC from control mucosa that was stimulated with 3 μM ionomycin (IONO) and followed by 100 μM CCH. E: group data of ΔISC with 3 μM IONO followed by 100 μM CCH in control mucosa. F: group data of CCH-induced ΔISC with and without 3 μM IONO administration. G: representative trace of ISC from mucosa exposed to DSS administered 3 μM IONO and 100 μM CCH. H: group data of ΔISC from DSS-colitis in response to 3 μM IONO followed by 100 μM CCH administration. I: group data of DSS-colitis CCH-induced ΔISC with and without 3 μM IONO administration. All presented bar graphs are summarized data that represent means ± SE. *P < 0.01, compared with control.