Table 2.

Summary of facility values in human eyes treated with 100 nM ET-1

Facility (C)	With TM	Trabeculotomy (Baseline)	ET-1 (100 nM)	ET-1 (100 nM) (Second Intervention)	DETA-NO (100 µM) + ET-1 (1 nM) (Second Intervention)
Control (n = 7)	0.23 ± 0.06*	0.43 ± 0.1	0.29 ± 0.2 (P < 0.01)†	0.32 ± 0.1 (P = 0.13)†	NA
Experimental (n = 7)	NA	0.54 ± 0.1	0.33 ± 0.2 (P < 0.01)†	NA	0.54 ± 0.4 (P < 0.05)†
P value (control vs. experimental)	NA	P = 0.87	P = 0.5	NA	P < 0.05
P value	NA	NA	NA	P < 0.05 (Trab vs. ET-1)	NA

ET-1, endothelin-1; NA, not applicable; TM, trabecular meshwork; Trab, trabeculotomized eyes.

^*This outflow facility data was obtained from 73 anterior segments that had been perfused and previously published by our laboratory (8, 13, 46, 55, 56).

^†P values indicated are a comparison of the indicated facility value with respect to the first facility value to the left of the indicated value on the table.