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. 2018 Aug 6;9:757. doi: 10.3389/fphar.2018.00757

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Copyright © 2018 Singh, Rai, Birla, Zahra, Kumar, Gedda, Tiwari, Patnaik, Singh and Singh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Estimation of activity of SOD and catalase. (A–C) Superoxide dismutase (SOD) and (B–D) catalase (CAT) activities measured in striatum and substantia nigra regions of the brain. MPTP injection caused significant increase in SOD and CAT activities in MPTP mice compared with the control group. CGA treatment in MPTP group increases SOD and CAT activities compared with the MPTP-injected animal group. Values are expressed as mean ± SEM (n = 6). ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001. CGA, chlorogenic acid; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SOD, superoxide dismutase; CAT, catalase; SEM, standard error of mean.