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. 2018 Aug 6;9:757. doi: 10.3389/fphar.2018.00757

FIGURE 6.

FIGURE 6

IHC of glial fibrillary acidic protein in the SN and striatum of mice. With 10 × magnifications after staining. The expression of GFAP-positive astrocytes was significantly increased in the SN and striatum of MPTP-injected mice compared with the control group, whereas CGA treatment decreased the expression of GFAP-positive astrocytes in MPTP+CGA group compared with the MPTP group. p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001. CGA, chlorogenic acid; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SN, substantia nigra; ST, striatum; GFAP, glial fibrillary acidic protein; SEM, standard error of mean; IFV, integrated fluorescent value.