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Inhibition of ataxia telangiectasia mutated kinase decreases acidic vesicular organelle formation in cardiac fibroblasts. Cardiac fibroblasts were treated with KU-55933 (KU; 100 µm) for 4 h and then stained with acridine orange dye. Left: orange fluorescent staining indicates acidic vesicular organelles. Right: quantitative analysis of acidic vesicular organelles in cardiac fibroblasts. n = 3. *P < 0.05 vs. the control (CTL) group.
