Mean blood pressures. A: mean blood pressure was similar in young (n = 21) and aged mice (n = 23) preuninephrectomy (solid bar) and postuninephrectomy (Nx) (open bar). Mean blood pressures were not different between young (solid line) and aged (dashed line) mice given water (n = 4 in young, n = 6 in aged) (B), hydralazine (n = 6 in young, n = 4 in aged) (C), enalapril (n = 6 in young, n = 6 in aged) (D), and losartan (n = 5 in young, n = 7 in aged) (E).