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. 2018 Feb 7;315(1):F97–F109. doi: 10.1152/ajprenal.00570.2017

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Fig. 8. — Immunoperoxidase staining for the prosenescent protein p16INK4a. Images of serial sections stained for p16INK4a (A) and renin (B) at D0. The dashed square indicates the region viewed at higher magnification. The juxtaglomerular compartment (JGC) cells do not stain for p16INK4a (A1) but do stain for renin (B1) (arrowheads represent same nuclei on serial sections). In aged mice, p16INK4a (C) overlaps with renin staining (D) and is present in glomerular cells. The dashed square indicates the region viewed at higher magnification for p16INK4a (C1) and renin (D1) (arrowheads represent same nuclei on serial sections). Scale bars = 20 μm.