Table 2.
Differentially expressed genes associated with lipid and carbohydrate metabolism and oxidative stress
| Transcript | Log2 FC | Uniprot ID | Gene Name | Pathway/Process |
|---|---|---|---|---|
| TRINITY_DN380627_c0_g1 | 1.73 | BMP8A_HUMAN | bone morphogenetic protein 8A (BMP8A) | brown adipose tissue thermogenesis |
| TRINITY_DN393979_c0_g1 | 1.63 | LEPR_PIG | leptin receptor (LEPR) | adipocytokine signaling pathway |
| TRINITY_DN339536_c10_g5 | 1.23 | GPX3_RAT | glutathione peroxidase 3 (GPX3) | thyroid hormone synthesis; Response to oxidative stress |
| TRINITY_DN379065_c5_g1 | −1.22 | PGM1_BOVIN | phosphoglucomutase-1 (PGM1) | pentose phosphate pathway |
| TRINITY_DN157252_c0_g1 | −1.33 | ECH1_PONAB | delta (3, 5)-delta (2, 4)-dienoyl-CoA isomerase, mitochondrial (ECH1) | fatty acid beta oxidation |
| TRINITY_DN276376_c0_g2 | −1.41 | GPX7_BOVIN | glutathione peroxidase 7 (GPX7) | thyroid hormone synthesis; lipid metabolism; response to oxidative stress |
| TRINITY_DN1029017_c0_g1 | −1.44 | TKT_HUMAN | transketolase (TKT) | pentose phosphate pathway |
| TRINITY_DN222849_c0_g2 | −1.46 | RARR2_PONAB | retinoic acid receptor responder protein 2 (RARRES2) | adipokine signaling |
| TRINITY_DN395199_c4_g12 | −1.53 | PLTP_HUMAN | phospholipid transfer protein (PTLP) | PPAR signaling pathway; Lipid transport |
| TRINITY_DN388710_c6_g4 | −1.59 | SCOT1_PIG | 3-oxoacid CoA-transferase 1 (OXCT1) | synthesis and degradation of ketone bodies |
| TRINITY_DN396178_c0_g6 | −1.60 | PXDNL_HUMAN | peroxidasin-like protein (PXDNL) | response to oxidative stress; hydrogen peroxide catabolic process |
| TRINITY_DN395661_c3_g1 | −1.76 | PCKGM_HUMAN | phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2) | glycolysis/gluco-neogenesis; PPAR signaling pathway |
| TRINITY_DN386920_c1_g3 | −1.86 | THIL_BOVIN | acetyl-CoA acetyltransferase 1 (ACAT1) | fatty acid degradation; synthesis and degradation of ketone bodies |
| TRINITY_DN292489_c1_g1 | −2.02 | IGF1_AILME | insulin-like growth factor 1 (IGF1) | PI3K-Akt, AMPK, HIF-1, FoxO signaling pathways |
| TRINITY_DN379917_c0_g4 | −2.14 | CR3L1_HUMAN | cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) | AMPK, PI3K-Akt signaling pathways; insulin secretion; thyroid hormone synthesis |
| TRINITY_DN344610_c2_g1 | −2.25 | MOT8_HUMAN | monocarboxylate transporter 8 (SLC16A2) | thyroid hormone signaling pathway |
| TRINITY_DN129339_c0_g1 | −2.37 | APOE_ZALCA | apolipoprotein E (APOE) | cholesterol metabolic process |
| TRINITY_DN385059_c1_g1 | −2.48 | C1QT6_RAT | complement C1q tumor necrosis factor-related protein 6 (C1QTNF6) | Type I diabetes mellitus |
| TRINITY_DN390074_c3_g1 | −3.19 | PI3R4_PONAB | phosphoinositide 3-kinase regulatory subunit 4 | apelin signaling pathway; autophagy |
| TRINITY_DN4732_c2_g5 | −3.97 | ACOD_HUMAN | stearoyl-CoA desaturase (delta-9-desaturase) (SCD) | AMPK signaling pathway |
FC, fold change (late/early fasting); adjusted P < 0.05.