Table 3.
Differentially expressed genes associated with amino acid and protein metabolism and extracellular matrix remodeling
| Transcript | Log2 FC | Uniprot ID | Gene Name | Pathway/Process |
|---|---|---|---|---|
| TRINITY_DN387928_c6_g2 | 2.37 | AOXB_MACFA | aldehyde oxidase 2 (AOX2) | Val, Leu, and Ile degradation; Tyr, Trp metabolism |
| TRINITY_DN327581_c0_g1 | −1.03 | P5CR2_BOVIN | pyrroline-5-carboxylate reductase 2 (PYCR2) | Arg and Pro metabolism |
| TRINITY_DN385444_c0_g1 | −1.09 | ADA12_HUMAN | disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) | metalloendopeptidase |
| TRINITY_DN392307_c1_g1 | −1.14 | MRC2_HUMAN | C-type mannose receptor 2 (MRC2) | collagen catabolic process |
| TRINITY_DN352091_c0_g1 | −1.18 | MMP23_BOVIN | matrix metalloproteinase-23 (MMP23) | metalloendopeptidase |
| TRINITY_DN252999_c0_g1 | −1.19 | CO6A3_HUMAN | collagen alpha-3(VI) chain (COL6A3) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN394004_c11_g4 | −1.26 | CO5A2_HUMAN | collagen alpha-2(V) chain (COL5A2) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN333936_c1_g2 | −1.30 | MMP14_RAT | matrix metalloproteinase-14 (MMP14) | metalloendopeptidase |
| TRINITY_DN375427_c15_g3 | −1.30 | CO4A2_HUMAN | collagen alpha-2(IV) chain (COL4A2) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN374050_c4_g1 | −1.37 | COFA1_HUMAN | collagen alpha-1(XV) chain (COL15A1) | protein digestion and absorption |
| TRINITY_DN341351_c0_g1 | −1.44 | PCOC1_HUMAN | procollagen C-endopeptidase enhancer 1 (PCOLCE) | proteolysis |
| TRINITY_DN394379_c13_g1 | −1.43 | ATS2_BOVIN | a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS2) | metalloendopeptidase |
| TRINITY_DN392463_c0_g1 | −1.54 | SARDH_MOUSE | sarcosine dehydrogenase, mitochondrial (SARDH) | Gly, Ser, and Thr metabolism |
| TRINITY_DN307780_c0_g1 | −1.59 | CO6A1_MOUSE | collagen alpha-1(VI) chain (COL6A1) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN648723_c0_g3 | −1.63 | A7E3A1_BOVIN | collagen alpha-3(V) chain (COL5A3) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN288724_c0_g2 | −1.64 | SAT1_PIG | diamine acetyltransferase 1 (SAT1) | Arg and Pro metabolism |
| TRINITY_DN384694_c1_g2 | −1.72 | AL4A1_HUMAN | delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (ALDH4A1) | Arg and Pro metabolism |
| TRINITY_DN648723_c0_g1 | −1.79 | CO5A3_HUMAN | collagen alpha-3(V) chain (COL5A3) | protein digestion and absorption |
| TRINITY_DN293757_c2_g1 | −1.88 | CO4A1_HUMAN | collagen alpha-1(IV) chain (COL4A1) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN383247_c0_g2 | −1.96 | CO6A2_HUMAN | collagen alpha-2(VI) chain (COL6A2) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN296911_c0_g1 | −1.99 | IVD_HUMAN | isovaleryl-CoA dehydrogenase, mitochondrial (IVD) | Val, Leu, and Ile degradation |
| TRINITY_DN370946_c0_g2 | −2.27 | CO5A1_HUMAN | collagen alpha-1(V) chain (COL5A1) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN392142_c1_g7 | −2.37 | CO1A2_CANLF | collagen alpha-2(I) chain (COL1A2) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN333370_c0_g1 | −2.44 | ELN_SHEEP | elastin (ELN) | protein digestion and absorption |
| TRINITY_DN394079_c2_g1 | −2.54 | CO6A6_HUMAN | collagen alpha-6(VI) chain (COL6A6) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN396844_c3_g1 | −2.56 | CO3A1_HUMAN | collagen alpha-1(III) chain (COL3A1) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN244979_c2_g2 | −2.88 | CO1A1_CANLF | collagen alpha-1(I) chain (COL1A1) | protein digestion and absorption; PI3K-Akt signaling pathway |
| TRINITY_DN154914_c0_g1 | −3.34 | KCRU_HUMAN | creatine kinase U-type, mitochondrial (CKMT1) | Arg and Pro metabolism |
| TRINITY_DN322676_c0_g1 | −4.13 | CBPZ_HUMAN | carboxypeptidase Z (CPZ) | metallocarboxy-peptidase |
FC, fold change (late/early fasting); adjusted P < 0.05.