Table 2.
Linear regression model for C3 expression
| Coefficients | SE | P Value | 95% CI | |
|---|---|---|---|---|
| Control lungs | ||||
| Age | −0.009 | 0.004 | 0.045 | (−0.017, −0.0002) |
| Sex | 0.088 | 0.143 | 0.540 | (−0.194, 0.370) |
| Smoking history | 0.018 | 0.094 | 0.186 | (−0.169, 0.204) |
| MUC5B genotype | 0.056 | 0.150 | 0.372 | (−0.241, 0.353) |
| IPF lungs | ||||
| Age | −0.006 | 0.007 | 0.366 | (−0.019, 0.007) |
| Sex | −0.157 | 0.114 | 0.171 | (−0.381, 0.068) |
| Smoking history | −0.097 | 0.097 | 0.321 | (−0.288, 0.095) |
| FVC | −0.001 | 0.003 | 0.850 | (−0.006, 0.005) |
| MUC5B genotype | 0.216 | 0.083 | 0.033 | (0.051, 0.380) |
Linear regression model for complement component 3 (C3) expression [10 − Δcycle threshold (ΔCT)] after controlling for age, sex, smoking history, and MUC5B genotype. IPF, idiopathic pulmonary fibrosis; CI, confidence interval; FVC, forced vital capacity.