Table 3.
The association C3 expression with HRCT findings
| HRCT: Lobe-Specific Honeycombing Score | High C3 | Low C3 | P Value |
|---|---|---|---|
| 0: Normal/none | 10 | 19 | |
| 1: Mild (1–25%) | 4 | 7 | |
| 2: Moderate (26–50%) | 2 | 3 | |
| 3: Marked (51–75%) | 1 | 1 | |
| 4: Severe (>75%) | 1 | 0 | Fisher’s exact test (0 vs. 1–4), P = 0.762 |
The comparison of high-resolution computed topography scan (HRCT) between cases in upper and lower quartile of complement component 3 (C3) expression (High C3 and Low C3, respectively). Extent of honeycombing in the lobe that mRNA was extracted from were determined by HRCT as previously described (36).