Fig. 5.

Prior CS exposure reduces bacteremia during pneumococcal pneumonia. A: schema depicting smoke exposure and infection. B: CS-exposed mice were less hypothermic than air-exposed mice, *by unpaired t-test. C: arterial hypoxemia was more severe in CS-exposed mice, in contrast to the survival benefit, *by unpaired t-test. D: bronchoalveolar lavage (BAL) protein, a gross measure of the permeability of the alveolar-capillary barrier, did not differ with regard to prior CS exposure 24 h following pneumococcal inoculation; P = 0.62 by unpaired t-test. E: pulmonary edema was not different in CS- and air-exposed mice at 24 h; P = 0.7 by unpaired t-test. F: prior CS exposure reduced recoverable pneumococci in blood by several orders of magnitude, *by Mann-Whitney. G: splenic pneumococci were also reduced by prior CS exposure, *by Mann-Whitney.