Fig. 2.

Gene-gene interaction network for AD. The network contains 1453 out of 1669 genes AD target genes that enriched within the 151 AD target pathways. The weight of an edge between two nodes is the number of pathways shared by both nodes. The larger the size of a node, the larger the number of AD candidate pathways including the gene (high PScore); the brighter the color, the larger number of AD candidate genes associated with gene (high SScore). 216 out of 1669 genes were not included in the network as they were not enriched within the top 151 AD candidate pathways.