Table 3.
ROC analysis for differentiating patients from controls.
| Brain regions | Area Under the Curve | Cut-off point | Sensitivity | Specificity |
|---|---|---|---|---|
| DIFFERENTIATING TREATMENT-RESISTANT PATIENTS FROM NON-TREATMENT-RESISTANT PATIENTS | ||||
| Right Angular Gyrus | 0.792 | −0.1746a | 70.59% (12/17) | 100% (17/17) |
| Left Postcentral Gyrus | 0.889 | −0.0966 | 94.12% (16/17) | 82.35% (14/17) |
| DIFFERENTIATING TREATMENT-RESISTANT PATIENTS FROM CONTROLS | ||||
| Left Inferior frontal gyrus, triangular part | 0.949 | −0.1112 | 100% (17/17) | 86.21% (25/29) |
| Right Inferior frontal gyrus, triangular part | 0.856 | −0.0564 | 70.59% (12/17) | 96.55% (28/29) |
| Right Middle frontal gyrus, orbital part | 0.872 | −0.1886 | 76.47% (13/17) | 82.76% (24/29) |
| Bilateral Superior medial frontal gyrus | 0.844 | 0.1511 | 88.24% (15/17) | 75.86% (22/29) |
| Right Fusiform Gyrus | 0.872 | −0.0830 | 94.12% (16/17) | 75.86% (22/29) |
| Left Middle Occipital Gyrus/ Middle Temporal Gyrus | 0.874 | 0.0899 | 100% (17/17) | 68.97% (20/29) |
| Right Superior Occipital Gyrus | 0.819 | −0.0412 | 76.47% (13/17) | 75.86% (22/29) |
| Right Superior Parietal Lobule | 0.832 | 0.0334 | 64.71% (11/17) | 93.10% (27/29) |
| Right Putamen | 0.797 | 0.1480 | 52.94% (9/17) | 96.55% (28/29) |
| Right Middle Occipital Gyrus/Middle Temporal Gyrus | 0.888 | 0.0391 | 94.12% (16/17) | 72.41% (21/29) |
| DIFFERENTIATING NON-TREATMENT-RESISTANT PATIENTS FROM CONTROLS | ||||
| Left Angular Gyrus | 0.852 | 0.0619 | 94.12% (16/17) | 68.97% (20/29) |
| Right Angular Gyrus | 0.872 | 0.0145 | 94.12% (16/17) | 72.41% (21/29) |
| Right Fusiform Gyrus | 0.903 | −0.1407 | 82.35% (14/17) | 93.10% (27/29) |
| Right Inferior Occipital Gyrus | 0.862 | 0.0203 | 70.59% (12/17) | 89.66% (26/29) |
| Left Postcentral Gyrus | 0.848 | 0.0176 | 82.35% (14/17) | 79.31% (23/29) |
| Left Middle Occipital Gyrus/ Middle Temporal Gyrus | 0.834 | 0.1591 | 94.12% (16/17) | 72.41% (21/29) |
a
By this cut-off point, the ReHo value in the right angular gyrus could correctly classify 12 of 17 treatment-resistant patients and 17 of 17 treatment-non-refractory patients, resulted in a sensitivity of 70.59% and a specificity of 100%. The meanings of other cut-off points were similar. ROC = receiver operating characteristic curves.