Table 1.
Vaccine-eligible cohort description and multivariable Cox proportional hazards survival analysis, site 1
| Survived (n=28 718) | All-cause deaths (n=367) | Diarrhoea-associated deaths (n=108) | Cox multivariable model, hazard ratio*(95% CI) | p value | |
|---|---|---|---|---|---|
| Rotavirus vaccine status | |||||
| 0 doses | 1724 (6%) | 65 (18%) | 10 (9%) | 1 (ref) | .. |
| 1 dose | 563 (2%) | 33 (9%) | 7 (7%) | .. | .. |
| 2 doses | 26 086 (91%) | 266 (72%) | 91 (84%) | 0·66 (0·34–1·28) | 0·22 |
| Missing | 345 (1%) | 3 (1%) | .. | .. | .. |
| Maternal marital status | |||||
| Married | 25 810 (90%) | 283 (77%) | 83 (77%) | 1 (ref) | .. |
| Single | 1567 (5%) | 39 (11%) | 11 (10%) | 1·91 (1·00–3·65) | 0·05 |
| Divorced or widowed | 1287 (5%) | 33 (9%) | 9 (8%) | 1·55 (0·74–3·27) | 0·25 |
| Died | 20 (0·1%) | 9 (2%) | 5 (5%) | 98·1 (39·5–243·6) | <0·001 |
| Missing | 34 (0·1%) | 3 (1%) | .. | .. | .. |
| Maternal education | |||||
| None | 3173 (11%) | 46 (13%) | 13 (12%) | 1 (ref) | .. |
| Primary | 21 963 (77%) | 280 (76%) | 82 (76%) | 1·12 (0·59–2·11) | 0·73 |
| Secondary or tertiary | 3543 (12%) | 37 (10%) | 13 (12%) | 0·95 (0·40–2·27) | 0·91 |
| Missing | 39 (0·1%) | 4 (1%) | .. | .. | .. |
| Water source | |||||
| Protected source | 23 525 (82%) | 283 (77%) | 81 (75%) | 1 (ref) | .. |
| Open source | 5167 (18%) | 81 (22%) | 27 (25%) | 1·42 (0·90–2·24) | 0·13 |
| Missing | 26 (0·1%) | 3 (1%) | .. | .. | .. |
| Toilet facility | |||||
| No facility | 5186 (18%) | 6 3 (17%) | 20 (19%) | 1 (ref) | .. |
| Some facility | 23 503 (82%) | 301 (82%) | 88 (81%) | 1·30 (0·76–2·21) | 0·34 |
| Missing | 29 (0·1%) | 3 (1%) | .. | .. | .. |
| House quality† | |||||
| Worst | 21 922 (76%) | 297 (81%) | 86 (80%) | 1 (ref) | .. |
| Middle | 4302 (15%) | 41 (11%) | 11 (10%) | 0·90 (0·48–1·72) | 0·76 |
| Best | 2464 (9%) | 26 (7%) | 11 (10%) | 1·71 (0·84–3·46) | 0·14 |
| Missing | 33 (0·1%) | 3 (1%) | .. | .. | .. |
| Season of birth | |||||
| Dry | 15 229 (53%) | 202 (55%) | 63 (58%) | 1 (ref) | .. |
| Rainy | 13 489 (47%) | 165 (45%) | 45 (42%) | 0·89 (0·60–1·31) | 0·55 |
| Mean (SD) | |||||
| Mother's age‡ | 26·0 (6·6) | 27·1 (7·3) | 27·9 (7·9) | .. | .. |
| Household assets§ | 1·5 (1·2) | 1·2 (1·2) | 1·1 (1·2) | 0·72 (0·59–0·87) | 0·001 |
Data are n (%), unless otherwise specified.
*
Hazard ratio of diarrhoea-associated death.
†
House quality is a composite of the construction materials used to make the roof, walls, and floor.
‡
Mother's age is standardised to be the age at birth of the child.
§
Household assets include bicycle, radio, ox cart and mobile phone.