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Mechanism of BCAAs-stimulated mTOR signaling and hepatocarcinogenesis. PI3K-Akt, phosohoinositide-3-kinase protein kinase B; p70S6K1, p70 S6 kinase 1; IRS-1, insulin receptor substrate; mTOR, mammalian target of rapamycin; BCAAs, branched-chain amino acids.
