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. Author manuscript; available in PMC: 2018 Aug 13.
Published in final edited form as: Biochemistry. 2018 Jul 17;57(30):4518–4525. doi: 10.1021/acs.biochem.8b00336

Table 3.

Pharmacokinetic properties of Zl-n-91

Dosing
route
T1/2
Range(h)
T1/2
(h)
Tmax
(h)
Cmax
(ng/mL)
AUC0-t
(ng/h/mL)
AUC0-m
(ng/h/mL)
Vz(F)
(L/kg)
CL(F)
(L/h/kg)
F (%)
PO 4–8 1.35 2 96.5 241 244 39.9 20.5 33.3
Dosing
route
T1/2
Range(h)
T1/2
(h)
C0 CL AUC0-t
(ng/h/mL)
AUC0-m
(ng/h/mL)
Vss MRTinf
(h)
IV 0.5–4 0.62 6030 6.87 725 728 2.31 0.34