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Effect of deletion of Sort1−/− gene on BDNF releasing pathways. Western blot analyses and their corresponding histogram quantification of the expression of proteins involved in the BDNF releasing pathways in brain extracts from WT and Sort1−/− mice. (A) Furin, (B) Plasmin, and (C) tPA. Histograms represented ratio of mean ± SEM of protein quantification from indicated number of brain samples. Mann–Whitney test, ∗p < 0.05; ∗∗p < 0.01, ns, non-significant.
