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. 2018 Jun 29;10(7):1011–1026. doi: 10.2217/epi-2017-0178

Figure 3. . Regression coefficients of the relationships between prenatal di-2-ethylhexyl phthalate metabolites and mean methylation of the MEG3 DMR with and without cell-type adjustment.

Figure 3. 

The methods included adjusting for cytological differential cell counts in a subset of cord blood samples (Yousefi 2015 [62]) and estimating cell-type proportions from CHAMACOS 450K cord blood DNA methylation data using adult (Solomon 2017 [47]) and cord blood (Bakulski 2016 [64]) flow sorted reference panels. The cord blood reference panel includes estimates of nucleated red blood cells (nRBCs).

*Not statistically significant at p < 0.05; all other presented relationships were significant at p < 0.05.

MBzP: Monobenzyl phthalate; MECPP: Mono(2-ethyl-5-carboxypentyl) phthalate; MEHP: Mono(2-ethylhexyl) phthalate; MEHHP: Mono(2-ethyl-5-hydroxyhexyl) phthalate; MEOHP: Mono(2-ethyl-5-oxohexyl) phthalate.