Skip to main content
. 2018 Aug 6;10:236. doi: 10.3389/fnagi.2018.00236

Table 2.

Bivariate correlations among the three inflammations markers in young and older participants.

IL-6 TNF-α CRP
IL-6 −0.03 0.28
TNF-α 0.41 0.18
CRP 0.52 0.34

Note. Correlation coefficients above the diagonal refer to young participants; correlation coefficients below the diagonal refer to older participants. We applied bias-corrected bootstrapping with 10,000 resampling to determine the significance of each correlation. Bold indicates significant age-group differences at p < 0.05. According to Fisher z-test, the correlation between interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) was significantly higher in older than young participants (z = −2.17, p = 0.03). In contrast, correlations between IL-6 and C-reactive protein (CRP; z = −1.35, p = 0.18) and between TNF-α and CRP (z = −0.80, p = 0.42) did not differ between the age groups.