Table 2. . Univariate cox proportional hazard model of overall survival using collected demographic and medical factors (n = 991).
Demographic and medical factors | p-value | Hazard ratio | 95% CI of HR | Generalized R2 (%) |
---|---|---|---|---|
Age at baseline (years) | <0.0001† | 1.023 | 1.017–1.029 | 5.66 |
Age ≥65 years | <0.0001† | 1.511 | 1.327–1.722 | 3.83 |
KPS score | <0.0001† | 0.973 | 0.968–0.978 | 15.89 |
KPS categories: | <0.0001† | 13.77 | ||
– 0–40 vs 80–100 | <0.0001 | 3.930 | 3.045–5.073 | |
– 50–70 vs 80–100 | <0.0001 | 1.576 | 1.307–1.899 | |
– 0–40 vs 50–70 | <0.0001 | 2.494 | 1.994–3.121 | |
– KPS <70 | <0.0001† | 1.968 | 1.677–2.311 | 9.71 |
PPS score | <0.0001† | 0.977 | 0.972–0.983 | 12.44 |
PPS categories: | <0.0001† | 10.60 | ||
– 0–40 vs 80–100 | <0.0001 | 3.159 | 2.343–4.258 | |
– 50–70 vs 80–100 | 0.0007 | 1.493 | 1.185–1.881 | |
– 0–40 vs 50–70 | <0.0001 | 2.116 | 1.639–2.731 | |
– PPS <70 | <0.0001† | 1.977 | 1.630–2.398 | 9.75 |
Gender | 0.0136† | 1.177 | 1.034–1.339 | 0.61 |
Patients coming from (hospital, home) | <0.0001† | 1.653 | 1.444–1.892 | 5.01 |
Ambulance | <0.0001† | 1.782 | 1.551–2.047 | 6.13 |
Previous radiotherapy | 0.4600 | 0.942 | 0.804–1.103 | 0.06 |
Postoperative | 0.0003† | 0.526 | 0.371–0.746 | 1.59 |
Primary cancer site: | 0.0006† | 2.22 | ||
– GI vs breast | <0.0001 | 1.840 | 1.366–2.479 | |
– GU vs breast | 0.0363 | 1.381 | 1.021–1.869 | |
– Lung vs breast | 0.0006 | 1.365 | 1.142–1.632 | |
– Other vs breast | 0.0607 | 1.345 | 0.987–1.834 | |
– Unknown vs breast | 0.0017 | 1.681 | 1.215–2.326 | |
Dose/fraction (cGy/fractions): | 0.0319† | 0.78 | ||
– 2000/5 vs other | 0.9975 | 1.000 | 0.754–1.328 | |
– 3000/10 vs other | 0.0543 | 0.680 | 0.459–1.007 | |
– 2000/5 vs 3000/10 | 0.0088 | 1.471 | 1.102–1.963 |
†p < 0.05.
KPS: Karnofsky performance status; PPS: Palliative performance scale.