Table 3. . Multivariate cox proportional hazard model of overall survival using demographic and medical factors (n = 666).
| Demographic and medical factors | Coefficient† | p-value | Hazard ratio | 95% CI of hazard ratio |
|---|---|---|---|---|
| Age ≥65 years | 0.309 | 0.0002‡ | 1.362 | 1.155–1.607 |
| KPS categories: | – | <0.0001‡ | – | – |
| – 0–40 vs 80–100 | 1.326 | <0.0001‡ | 3.767 | 2.899–4.894 |
| – 50–70 vs 80–100 | 0.494 | <0.0001‡ | 1.638 | 1.356–1.979 |
| – 0–40 vs 50–70 | – | <0.0001‡ | 2.299 | 1.821–2.887 |
| Postoperative | -0.675 | 0.0005‡ | 0.509 | 0.347–0.747 |
| Primary cancer site: | – | 0.0025‡ | – | – |
| – GI vs breast | 0.728 | 0.0001‡ | 2.070 | 1.426–3.005 |
| – GU vs breast | 0.506 | 0.0081‡ | 1.659 | 1.141–2.413 |
| – Lung vs breast | 0.304 | 0.0087‡ | 1.356 | 1.080–1.702 |
| – Other vs breast | 0.188 | 0.3216 | 1.207 | 0.832–1.751 |
| – Unknown vs breast | 0.483 | 0.0339‡ | 1.620 | 1.037–2.531 |
Generalized R2 = 20.21%
†In the Cox proportional hazard regression analysis, a covariate with a positive coefficient is associated with worse survival prognosis while covariate with a negative coefficient is associated with improved survival prognosis.
‡p < 0.05.
GI: Gastrointestinal; GU: Genitourinary; KPS: Karnofsky performance status.