Table 1. . Clinical features of included cases.
| Features | Patients (n) | Patients (% of n) |
|---|---|---|
| Clinicopathological features at breast cancer diagnosis | ||
| Patients | 215 | |
| Median age, years (min–max) | 47 (24–80) | |
| Clinical stage | ||
| I–II | 71 | 33.0 |
| III | 126 | 58.6 |
| Unknown | 18 | 8.4 |
| Histology | ||
| Ductal | 209 | 97.2 |
| Lobular | 2 | 0.9 |
| Medullary | 2 | 0.9 |
| Mixto | 2 | 0.9 |
| Histologic grade | ||
| 1–2 | 75 | 34.9 |
| 3 | 135 | 62.8 |
| Unknown | 5 | 2.3 |
| Estrogen receptor | ||
| Negative | 134 | 62.3 |
| Positve | 75 | 34.9 |
| Unknown | 6 | 2.8 |
| HER2 status | ||
| Negative | 157 | 73.0 |
| Positve | 55 | 25.6 |
| Unknown | 3 | 1.4 |
| Phenotype | ||
| Luminal-A | 20 | 9.3 |
| Luminal-B | 59 | 27.4 |
| HER2 enriched | 44 | 20.5 |
| Triple negative | 83 | 38.6 |
| Unknown | 9 | 4.2 |
| Signs and symptoms at brain metastasis | ||
| ECOG at brain metastasis time | ||
| 1 | 121 | 56.3 |
| 2 | 63 | 29.3 |
| 3–4 | 15 | 7.0 |
| Unknown | 16 | 7.4 |
| CT scan image features | ||
| Number of brain lesions | ||
| 1–3 | 118 | 54.9 |
| >3 | 77 | 35.8 |
| Unknown | 1 | 0.5 |
| Carcinomatosis (image or cytology result) | 32 | 14.9 |
| Median diameter of largest lesion, cm (min–max) | 2.25 (0.3–9.0) | |
| Edema | 174 | 80.9 |
| Unknown | 20 | 9.3 |
| Necrosis | 32 | 14.9 |
| Unknown | 21 | 9.8 |
| Hemorrhage | 10 | 4.7 |
| Unknown | 20 | 9.3 |
| Largest lesion shape | ||
| Nodular | 120 | 55.8 |
| Ringed | 34 | 15.8 |
| Lobulated | 11 | 5.1 |
| Irregular | 10 | 4.7 |
| Cystic | 16 | 7.4 |
| Calcifications | 3 | 1.4 |
| Unknown | 21 | 9.8 |
ECOG: Eastern Cooperative Oncology Group.