Table 2. . Features related to time to CNS metastases.

Features	Patients (n)	Brain metastasis at 2 years (%)	p-value
Age (years):			0.1044
– ≤45	35	40.7
– >45	55	50.5
Clinical stage:			<0.001
– I–II	48	72.7
– III	38	31.4
Histological grade:			0.0011
– 1–2	41	56.9
– 3	48	38.1
Estrogen receptor status:			<0.001
– Positive	51	70.8
– Negative	41	32.8
HER2 status:			0.0472
– Positive	19	38.0
– Negative	74	49.3
Molecular subtype:			<0.001
– Luminal	52	69.3
– Nonluminal	38	31.9
Molecular subtype:			0.0002
– Nontriple negative	67	57.8
– Triple negative	23	29.5