Table 1. Replicate CLintapp Data for Identical Compounds Tested at Least Twice in MSD Metabolic Stability Assays.
WH rat |
human |
|||||||
---|---|---|---|---|---|---|---|---|
assay | n | >3-fold (%) | >10-fold (%) | fold error | n | >3-fold (%) | >10-fold (%) | fold error |
Heps | 471 | 7 | 1.5 | 2.23 | 594 | 5 | 0.2 | 1.65 |
Mics | 427 | 12 | 0.9 | 1.96 | 449 | 10 | 0.7 | 1.93 |