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. 2018 Jul 19;9(8):843–847. doi: 10.1021/acsmedchemlett.8b00259

Table 1. Replicate CLintapp Data for Identical Compounds Tested at Least Twice in MSD Metabolic Stability Assays.

  WH rat
human
assay n >3-fold (%) >10-fold (%) fold error n >3-fold (%) >10-fold (%) fold error
Heps 471 7 1.5 2.23 594 5 0.2 1.65
Mics 427 12 0.9 1.96 449 10 0.7 1.93