Table 3.
PharMetrics Database: Lung NET Incidence Rate, Cases per Million Person-Yearsa
| No. Of Cases Per Million Person-Years (Numerator/Denominator) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2011 | 2012 | 2013 | 2014 | ||||||||||
| Gender | Age | ||||||||||||
| Female | 18–24 | 2.5 | (2 | /809,900) | 1.2 | (1 | /803,203) | 0.0 | (0 | /844,220) | 1.5 | (1 | /670,429) |
| 25–34 | 5.5 | (5 | /915,829) | 4.7 | (4 | /846,136) | 3.5 | (3 | /851,694) | 1.5 | (1 | /659,964) | |
| 35–44 | 2.2 | (3 | /1,387,525) | 7.0 | (9 | /1,280,702) | 12.8 | (16 | /1,249,676) | 10.3 | (10 | /972,515) | |
| 45–54 | 10.0 | (19 | /1,902,036) | 18.9 | (33 | /1,747,518) | 18.9 | (32 | /1,688,747) | 19.5 | (25 | /1,282,436) | |
| 55–64 | 37.6 | (68 | /1,809,406) | 47.4 | (81 | /1,708,362) | 55.4 | (94 | /1,697,399) | 51.9 | (67 | /1,290,342) | |
| All Female | 14.2 | (97 | /6,824,696) | 20.0 | (128 | /6,385,921) | 22.9 | (145 | /6,331,736) | 21.3 | (104 | /4,875,686) | |
| Male | 18–24 | 1.2 | (1 | /828,261) | 3.6 | (3 | /823,432) | 2.3 | (2 | /875,326) | 1.4 | (1 | /698,342) |
| 25–34 | 2.4 | (2 | /839,247) | 1.2 | (1 | /800,680) | 0.0 | (0 | /818,984) | 1.5 | (1 | /662,957) | |
| 35–44 | 5.5 | (7 | /1,266,850) | 5.1 | (6 | /1,185,774) | 3.4 | (4 | /1,164,816) | 6.4 | (6 | /935,200) | |
| 45–54 | 10.5 | (18 | /1,713,588) | 11.9 | (19 | /1,599,135) | 12.8 | (20 | /1,556,840) | 8.2 | (10 | /1,218,043) | |
| 55–64 | 28.7 | (47 | /1,637,294) | 20.6 | (32 | /1,552,538) | 23.2 | (36 | /1,551,338) | 26.3 | (32 | /1,216,691) | |
| All Male | 11.9 | (75 | /6,285,240) | 10.2 | (61 | /5,961,559) | 10.4 | (62 | /5,967,304) | 10.6 | (50 | /4,731,233) | |
| All Gender | 18–24 | 1.8 | (3 | /1,638,161) | 2.5 | (4 | /1,626,635) | 1.2 | (2 | /1,719,546) | 1.5 | (2 | /1,368,771) |
| 25–34 | 4.0 | (7 | /1,755,076) | 3.0 | (5 | /1,646,816) | 1.8 | (3 | /1,670,678) | 1.5 | (2 | /1,322,921) | |
| 35–44 | 3.8 | (10 | /2,654,375) | 6.1 | (15 | /2,466,476) | 8.3 | (20 | /2,414,492) | 8.4 | (16 | /1,907,715) | |
| 45–54 | 10.2 | (37 | /3,615,624) | 15.5 | (52 | /3,346,653) | 16.0 | (52 | /3,245,587) | 14.0 | (35 | /2,500,479) | |
| 55–64 | 33.4 | (115 | /3,446,700) | 34.7 | (113 | /3,260,900) | 40.0 | (130 | /3,248,737) | 39.5 | (99 | /2,507,033) | |
| All Patients | 13.1 | (172 | /13,109,936) | 15.3 | (189 | /12,347,480) | 16.8 | (207 | /12,299,040) | 16.0 | (154 | /9,606,919) | |
| Adjusted Rate (No. Of Cases Per Million Person-Years)b | |||||||||||||
| All Femalec | 12.8 | 18.0 | 20.6 | 19.3 | |||||||||
| All Maled | 10.6 | 9.3 | 9.3 | 9.6 | |||||||||
| All Patientse | 11.7 | 13.8 | 15.2 | 14.6 | |||||||||
a Cases (adults with ≥1 inpatient or ≥ 2 outpatient claims for lung NET in listed year and continuous enrollment in year listed and two years prior) ÷ number of members with continuous enrollment in same period
bAPC (95% CI; P value): female 14.7% (−12.9–51.2; 0.165); male −2.9% (−13.8–9.4; 0.395); all patients 7.8% (−5.7–23.4; 0.137)
cAdjusted based on distribution of age among male from both databases in 2014
dAdjusted based on distribution of age among female from both databases in 2014
eAdjusted based on combined distribution of age among male from both databases in 2014