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. Author manuscript; available in PMC: 2019 Jun 15.
Published in final edited form as: ACS Chem Biol. 2018 May 17;13(6):1610–1620. doi: 10.1021/acschembio.8b00230

Figure 6.

Figure 6

A ΔcstR mutant strain deficient in colonization of silicone implants in a murine model of CAUTI. Graphs represent bacterial titers in log scale recovered from the (a) bladders and (b) silicone implants from female C57BL/6Ncr mice infected with OG1RF wild-type or ΔcstR mutant for 24 h. Horizontal dashed lines represent the limits of detection for viable bacteria. Each symbol represents the value for an individual mouse, and each experiment was done three times with four or five mice for each strain. The horizontal bars indicate the median value for each group of mice. Values that are significantly different by the Mann–Whitney U test are indicated as follows: *p < 0.05; ns, difference not statistically significant.