Table 2.
Differences in activation between physically maltreated adolescents, psychiatric control adolescents and healthy control adolescents for fear v. fixation and fear v. happy
| Emotion contrast | Subject contrast | Brain regions of activation | Brodmann's area | Cluster level | Peak MNI coordinates | Voxel level Z value |
|
|---|---|---|---|---|---|---|---|
| No. of Voxels | p (corr.) | ||||||
| Fear v. fixation | CM > HC | B MFG, ACC, SFG, IFG, preCG, caudate body | 6/8/9/10/24/32/47 | 4615 | 0.002 | −6, 52, 8 | 3.93 |
| −34, 6, 30 | 3.61 | ||||||
| 12, 52, 8 | 3.6 | ||||||
| Fear v. happy | CM > HC | B ACC, MFG, SFG, IFG, preCG, caudate body | 6/8/9/10/24/32/47 | 7541 | <0.001 | 10, 18, 22 | 3.86 |
| 18, 30, 20 | 3.82 | ||||||
| 32, 24, 22 | 3.78 | ||||||
ACC, Anterior cingulate cortex; B, Bilateral; CM, childhood maltreatment; HC, healthy controls; IFG, inferior frontal gyrus; MFG, medial frontal gyrus; MNI, Montreal Neurological Institute; preCG, precentral gyrus; SFG, superior frontal gyrus.
p value is <0.05 FWER corrected.