Table 2.
Binary logistic regression analysis of factors associated with starting paliperidone palmitate compared with other antipsychotic LAI, n = 1281
| Factor | Group | Number in sample | Percentage started on paliperidone palmitate (%) | Unadjusted odds ratio | 95% confidence interval, p value | aAdjusted odds ratio | 95% confidence interval, p value |
|---|---|---|---|---|---|---|---|
| Age | Age 16–25 years | 243 | 33.7 | 0.95 | 0.67–1.34, p = 0.75 | 0.99 | 0.68–1.45, p = 0.97 |
| 26–35 | 337 | 35.0 | Reference | Reference | |||
| 36–45 | 301 | 30.9 | 0.83 | 0.60–1.16, p = 0.27 | 0.79 | 0.55–1.13, p = 0.20 | |
| 46–55 | 280 | 36.4 | 1.06 | 0.76–1.48, p = 0.72 | 0.98 | 0.69–1.41, p = 0.92 | |
| 56–65 | 120 | 29.2 | 0.76 | 0.49–1.20, p = 0.24 | 0.71 | 0.43–1.19, p = 0.20 | |
| Gender | Female | 513 | 37.6 | 1.35 | 1.07–1.71, p = 0.01 | 1.37 | 1.04–1.79, p = 0.02 |
| Male | 768 | 30.9 | Reference | Reference | |||
| Ethnicity | White | 501 | 28.9 | 0.67 | 0.52–0.86, p = 0.002 | 1.06 | 0.79–1.41, p = 0.71 |
| Asian | 71 | 33.8 | 0.84 | 0.50–1.41, p = 0.51 | 1.27 | 0.72–2.23, p = 0.41 | |
| Black | 597 | 37.9 | Reference | Reference | |||
| Other ethnic group | 112 | 31.3 | 0.75 | 0.48–1.15, p = 0.18 | 1.04 | 0.64–1.67, p = 0.88 | |
| Marital status | Married/cohabiting | 129 | 41.1 | 1.38 | 0.95–2.01, p = 0.09 | 1.34 | 0.89–2.03, p = 0.16 |
| Divorced/separated | 121 | 38.8 | 1.26 | 0.85–1.86, p = 0.25 | 1.19 | 0.77–1.84, p = 0.43 | |
| Single | 960 | 33.5 | Reference | Reference | |||
| Widowed | 13 | 7.7 | 0.17 | 0.02–1.28, p = 0.08 | 0.19 | 0.02–1.59, p = 0.13 | |
| Marital status unknown | 58 | 12.1 | 0.27 | 0.12–0.61, p = 0.001 | 0.73 | 0.31–1.75, p = 0.48 | |
| Diagnosis | Schizophrenia and related | 743 | 37.8 | Reference | Reference | ||
| Schizoaffective | 77 | 40.3 | 1.11 | 0.69–1.79, p = 0.68 | 0.89 | 0.54–1.49, p = 0.67 | |
| Bipolar disorder | 27 | 44.4 | 1.32 | 0.61–2.85, p = 0.49 | 1.13 | 0.49–2.62, p = 0.78 | |
| Psychotic Depression | 84 | 26.2 | 0.58 | 0.35–0.97, p = 0.04 | 0.61 | 0.35–1.04, p = 0.07 | |
| Drug-induced psychosis | 15 | 53.3 | 1.88 | 0.67–5.24, p = 0.23 | 1.88 | 0.63–5.62, p = 0.26 | |
| Other psychosis | 335 | 22.7 | 0.48 | 0.36–0.65, p < 0.001 | 0.54 | 0.39–0.74, p < 0.001 | |
| Location | Inpatient | 694 | 42.9 | Reference | Reference | ||
| Outpatient | 587 | 22.5 | 0.39 | 0.30–0.49, p < 0001 | 0.45 | 0.34–0.60, p < 0.001 |
a
Adjusted for age, gender, ethnicity, marital status, diagnosis, location of starting LAI, number of admissions in the 3 years prior to starting LAI, and borough of residence.