Table 2.
Mean (s.e.m.) absolute concentrations (μmol/g) glutamate and glutamine, corrected for GM, WM and CSF content in ACC, OCC and PUT
| Depressed patients | Healthy controls | t value, p | |
|---|---|---|---|
| Glutamine (ACC) | 3.48 (0.12) | 3.21 (0.07) | t = 1.80, p = 0.075 |
| Glutamine (OCC) | 6.19 (0.11) | 6.30 (0.12) | t = −0.73, p = 0.47 |
| Glutamine (PUT) | 4.73 (0.12) | 4.17 (0.11) | t = 3.30; p < 0.001 |
| Glutamate (ACC) | 9.11 (0.14) | 9.24 (0.14) | t = −0.66, p = 0.51 |
| Glutamate (OCC) | 5.61 (0.10) | 5.77 (0.10) | t = −1.12, p = 0.26 |
| Glutamate (PUT) | 8.73 (0.11) | 8.73 (0.13) | t = 0.003, p = 0.99 |