Table 5.

Treatment-emergent adverse event (TEAE) profiles after co-administration of candesartan and amlodipine and after administration of each drug alone in healthy subjects

Symptom and sign	Combination (n=20)	Alone (n=20)
Part 1 (candesartan)
Blood pressure diastolic decreased	3 (3)	2 (2)
Dizziness postural	1 (1)	2 (2)
Headache	2 (2)	–
Somnolence	2 (2)	–
Part 2 (amlodipine)
Palpitations	1 (1)	1 (1)
Blood pressure diastolic decreased	6 (6)	–
Headache	1 (1)	4 (4)
Rhinorrhoea	–	2 (2)

Note: TEAEs that were reported at least twice are presented as number of subjects (number of events).