Table 5.
Univariate and multivariate regression analyses of preoperative, operative and early postoperative risk factors for postoperative AKI.
| Variables | Postoperative AKI | |||
|---|---|---|---|---|
| Unadjusted OR (95% CI) |
P | Adjusted OR (95% CI) |
P | |
| Gender | 0.91 (0.48-1.73) | 0.87 | __ | __ |
| Age | 1.02 (0.99-1.05) | 0.16 | __ | __ |
| Ejection fraction (%) | 0.98 (0.95-1.01) | 0.15 | __ | __ |
| Diabetes mellitus | 1.70 (0.97-2.98) | 0.17 | __ | __ |
| Hypertension | 1.25 (0.70-2.24) | 0.46 | __ | __ |
| Hyperlipidaemia | 0.83 (0.47-1.45) | 0.51 | __ | __ |
| Smoking | 1.47 (0.84-2.58) | 0.18 | __ | __ |
| BMI | 1.05 (0.98-1.12) | 0.20 | __ | __ |
| Preoperative creatinine (mg/dl) | 2464.06 (383.62-15827.07) | 0.0001 | 4097.94 (52.93-317299.77) | 0.0001 |
| Preoperative urea (mg/dl) | 1.12 (1.07-1.17) | 0.0001 | 1.05 (0.94-1.18) | 0.37 |
| Preoperative platelet (x103/µL) | 1.00 (0.99-1.01) | 0.12 | __ | __ |
| Preoperative CRP (mg/l) | 3.17 (2.12-4.75) | 0.0001 | 2.71 (1.16-6.35) | 0.02 |
| Preoperative hemoglobin (mg/dl) | 1.13 (0.92-1.37) | 0.24 | __ | __ |
| Preoperative leukocyte (x103/µL) | 0.99 (0.98-1.00) | 0.44 | __ | __ |
| Preoperative NLR | 1.76 (1.38-2.23) | 0.0001 | 0.45 (0.22-0.95) | 0.04 |
| Preoperative PLR | 1.05 (1.03-1.07) | 0.0001 | 1.06 (1.02-1.10) | 0.002 |
| Postoperative first day platelet (x103/µL) | 1.32 (1.08-1.62) | 0.007 | 1.00 (0.99-1.01) | 0.20 |
| Postoperative first day hemoglobin (mg/l) | 0.90 (0.70-1.16) | 0.42 | __ | __ |
| Postoperative first day leukocyte (x103/µL) | 0.97 (0.92-1.02) | 0.0001 | 1.01(0.99-1.03) | 0.03 |
| Postoperative first day CRP (mg/l) | 1.25 (1.17-1.33) | 0.0001 | 1.19 (1.02-1.36) | 0.02 |
| Postoperative first day NLR | 2.46 (1.97-3.07) | 0.0001 | 3.04 (1.51-6.10) | 0.002 |
| Postoperative first day PLR | 1.09 (1.07-1.12) | 0.0001 | 1.06 (1.01-1.10) | 0.01 |
| Aortic cross clamp time | 1.01 (0.99-1.03) | 0.48 | __ | __ |
| Number of distal anastomoses | 1.11 (0.82-1.49) | 0.50 | __ | __ |
| CPB time | 1.01 (0.99-1.03) | 0.37 | __ | __ |
| Intubation time | 1.44 (1.27-1.63) | 0.0001 | 1.64 (1.15-2.33) | 0.006 |
| Use of blood products | 1.13 (0.65-1.97) | 0.67 | __ | __ |
| Use of inotropic support | 2.28 (1.16-4.48) | 0.02 | 0.31(0.08-2.29) | 0.17 |
| Amount of drainage | 1.00 (0.99-1.01) | 0.18 | __ | __ |
AF=atrial fibrillation; BMI = body mass index; CPB=cardiopulmonary bypass; CRP=C-reactive protein; NLR=neutrophil to lymphocyte ratio; PLR=platelet to lymphocyte ratio