Table 1.
Myocytolysis | PMNL infiltration | Myofibrillar edema | Focal hemorrhage | |
---|---|---|---|---|
C-1 | 1 | 1 | 1 | 1 |
C-2 | 1 | 1 | 1 | 1 |
C-3 | 1 | 1 | 1 | 1 |
C-4 | 1 | 1 | 1 | 1 |
C-5 | 1 | 1 | 1 | 1 |
C-6 | 1 | 1 | 1 | 1 |
C-7 | 1 | 1 | 1 | 1 |
C-8 | 1 | 1 | 1 | 1 |
I/R -1 | 1 | 2 | 1 | 2 |
I/R -2 | 1 | 2 | 2 | 2 |
I/R -3 | 1 | 1 | 1 | 2 |
I/R -4 | 1 | 1 | 2 | 2 |
I/R -5 | 1 | 1 | 2 | 3 |
I/R -6 | 1 | 1 | 2 | 2 |
I/R -7 | 1 | 1 | 2 | 2 |
I/R -8 | 1 | 1 | 1 | 3 |
I/R +A-1 | 1 | 1 | 1 | 1 |
I/R +A -2 | 1 | 1 | 1 | 1 |
I/R +A -3 | 1 | 1 | 1 | 1 |
I/R +A -4 | 1 | 1 | 1 | 1 |
I/R +A -5 | 1 | 1 | 2 | 2 |
I/R +A -6 | 1 | 1 | 1 | 1 |
I/R +A -7 | 1 | 1 | 1 | 1 |
I/R +A -8 | 1 | 1 | 1 | 1 |
C=control; I/R=ischemia-reperfusion; I/R+A=ischemia-reperfusion + Acetaminophen; PMNL=polymorphonuclear leukocyte Histopathologic scoring was rated as +1 = no change; +2 = light injury; +3 = moderate injury; +4 = diffuse injury.