Figure 4.

Silencing of CD164 inhibited the migration and invasion of tumor cells by regulating MMP2 and MMP9. A, Wound and healing assay was used to investigate the influence of CD164 on tumor migration. The distance between edges in shRNA group were wider than controls (P < .05). B, Transwell array showed that the ability of invasion in shRNA group was decreased significantly (P < .05). C and D, The expression of migration and invasion‐related proteins MMP2 and MMP9 was reduced in shRNA group (P < .05)