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. 2018 Jul 7;7(8):3889–3898. doi: 10.1002/cam4.1581

Figure 1.

Figure 1

Diagnostic performance of CSF Npt concentration. A, Box plot of CSF neopterin concentrations in patients with PCNSL, other brain tumors (OBT), and inflammatory diseases (ID). Data are presented as median and range. P < .001 for PCNSL vs OBT and PCNSL vs ID. B, Receiver operating characteristic (ROC) curve was used to determine the cutoff value of neopterin level in the CSF to distinguish PSNCL from other brain tumor types in 65 patients with brain tumors. The area under the curve (AUC) was determined. C, Representative MR images and Npt concentrations in CSF in a true‐positive PCNSL case (C1), a false‐positive PCNSL case (C2), a false‐negative PCNSL case (C3), and a true‐negative PCNSL case (C4). C1 Npt: 28.291 ng/mL; C2 Npt: 7.229 ng/mL; C3 Npt: 23.976 ng/mL; and C4 Npt: 5.118 ng/mL