Table 1.
Comparison of baseline characteristics by various circumferential resection margins
| Variable | Distance to circumferential resection margin | P value | ||||
|---|---|---|---|---|---|---|
| 0‐1.0 mm | 1.1‐2.0 mm | 2.1‐5.0 mm | 5.1‐10.0 mm | >10.0 mm | ||
| AJCC stage | ||||||
| Stage I | 620 (32.9%) | 214 (11.3%) | 355 (18.8%) | 166 (8.8%) | 531 (28.2%) | <0.001 |
| Stage II | 1071 (39.3%) | 320 (11.8%) | 428 (15.7%) | 274 (10.1%) | 630 (23.1%) | |
| Stage III | 1772 (41.1%) | 482 (11.2%) | 671 (15.6%) | 426 (9.9%) | 957 (22.2%) | |
| Stage IV | 769 (60.8%) | 110 (8.7%) | 127 (10.0%) | 84 (6.6%) | 174 (13.8%) | |
| Tumor size | ||||||
| ≤5 cm | 2379 (37.9%) | 704 (11.2%) | 1039 (16.6%) | 602 (9.6%) | 1549 (24.7%) | <0.001 |
| >5 cm | 1499 (47.7%) | 315 (10.0%) | 444 (14.1%) | 283 (9.0%) | 601 (19.1%) | |
| Unknown | 354 (46.2%) | 107 (14.0%) | 88 (12.8%) | 65 (8.5%) | 142 (18.5%) | |
| Age at diagnosis (y) | ||||||
| ≤60 | 1903 (41.4%) | 504 (11.0%) | 700 (15.2%) | 433 (9.4%) | 1061 (23.1%) | 0.757 |
| >60 | 2329 (41.7%) | 622 (11.1%) | 881 (15.8%) | 517 (9.3%) | 1231 (22.1%) | |
| Race | ||||||
| White | 3388 (40.9%) | 932 (11.2%) | 1313 (15.8%) | 779 (9.4%) | 1876 (22.6%) | <0.001 |
| Black | 408 (51.3%) | 84 (10.6%) | 104 (13.1%) | 54 (6.8%) | 145 (18.2%) | |
| Other | 436 (39.7%) | 110 (10.0%) | 164 (14.9%) | 117 (10.7%) | 271 (24.7%) | |
| Gender | ||||||
| Male | 2543 (42.0%) | 688 (11.4%) | 907 (15.0%) | 562 (9.3%) | 1354 (22.4%) | 0.287 |
| Female | 1689 (40.9%) | 438 (10.6%) | 674 (16.3%) | 388 (9.4%) | 938 (22.7%) | |
| Year of diagnosis | ||||||
| 2010 | 895 (48.5%) | 225 (12.2%) | 290 (15.7%) | 157 (8.5%) | 280 (15.2%) | <0.001 |
| 2011 | 874 (42.9%) | 229 (11.3%) | 317 (15.6%) | 172 (8.5%) | 443 (21.8%) | |
| 2012 | 873 (41.3%) | 216 (10.2%) | 325 (15.4%) | 208 (9.8%) | 491 (23.2%) | |
| 2013 | 803 (38.8%) | 220 (10.6%) | 317 (15.3%) | 213 (10.3%) | 516 (24.9%) | |
| 2014 | 787 (37.2%) | 236 (11.1%) | 332 (15.7%) | 200 (9.4%) | 562 (26.5%) | |
| Grade | ||||||
| Grade I | 279 (43.7%) | 75 (11.8%) | 110 (17.2%) | 61 (9.6%) | 113 (17.7%) | <0.001 |
| Grade II | 2835 (38.1%) | 859 (11.5%) | 1217 (16.3%) | 730 (9.8%) | 1806 (24.3%) | |
| Grade III | 725 (55.6%) | 116 (8.9%) | 165 (12.7%) | 88 (6.7%) | 210 (16.1%) | |
| Grade IV | 170 (60.1%) | 25 (8.8%) | 27 (9.5%) | 18 (6.4%) | 43 (15.2%) | |
| Unknown | 223 (43.8%) | 51 (10.0%) | 62 (12.2%) | 53 (10.4%) | 120 (23.6%) | |