Figure 1.

IQUB is significantly upregulated in human breast cancer tissues and cells. A, IQUB protein expression (the brown staining areas) was increased in breast cancer, which was detected in 110 cases of human breast cancer tissue microarray by immunohistochemistry. B, The expression of IQUB in poor differentiation of breast cancer tissues was higher than that in well differentiation of breast cancer tissues. C, IQUB mRNA expression was upregulated in breast cancer tissues (16/20) than paired normal breast tissues which was analyzed by RT‐qPCR (x‐axis represent 20 pairs of tissue samples). D, IQUB mRNA and protein expression were detected by RT‐qPCR and Western blotting in normal breast cell line MCF‐10A and breast cancer cell lines MCF‐7 and MDA‐MB‐231. Values represent the mean ± SD from 3 independent measurements. **P < .01, ***P < .001