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. Author manuscript; available in PMC: 2019 Jan 18.
Published in final edited form as: Nature. 2018 Jul 18;559(7715):617–621. doi: 10.1038/s41586-018-0344-3

Figure 4. Undermining outer-membrane integrity reduces survival during mechanical perturbation and L-form proliferation.

Figure 4

a) Cell lysis versus time under chemical perturbation to outer membrane. Shock: 400-mM oscillations with 2-min period. No cells died in the absence of both oscillatory shock and outer membrane perturbation (n=1000 cells). t25, time at which 25% of cells had lysed.

b) Time at which 25% of cells had lysed under chemical or genetic perturbations (ratio to untreated wild-type).

c) Concentration of viable L-forms in overnight cultures under chemical or genetic perturbations to outer membrane (ratio to untreated wild-type, 1 experiment).