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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Am Coll Surg. 2018 Apr 6;227(2):238–246.e2. doi: 10.1016/j.jamcollsurg.2018.03.041

Table 3.

Positive Predictive Values of Imaging Predictor Variables and Staging Systems



n
Intraoperative finding C-index

 Resected
Distant
metastasis
Locally
advanced
n % n % n %
Suspicious LN on imaging 0.63
 None 290 192 66 48 17 50 17
 N1 199 89 45 68 34 42 21
 N2 55 21 38 24 44 10 18
PV involvement on imaging 0.64
 None 268 180 67 51 19 37 14
 Unilateral 215 109 51 63 29 43 20
 Bilateral or main stem 62 14 23 26 42 22 35
HA involvement on imaging 0.65
 None 330 220 67 66 20 44 13
 Unilateral 169 73 43 52 31 44 26
 Bilateral or main stem 31 2 6 17 55 12 39
Bismuth classification on imaging* 0.62
 Left or right hepatic duct only 35 29 83 5 14 1 3
 B1 69 48 70 14 20 7 10
 B2 55 31 56 14 26 7 10
 B3A (right) 172 92 53 51 30 29 17
 B3B (left) 109 61 56 28 26 20 18
 B4 126 48 38 39 31 39 31
cTNM staging 0.68
 1 31 24 77 3 10 4 13
 2 113 86 76 17 15 10 9
 3 208 122 59 56 27 30 14
 4 214 77 36 75 35 62 29
Blumgart T-staging 0.67
 T1 207 148 71 37 18 22 11
 T2 168 97 58 48 28 23 14
 T3 188 64 34 65 35 59 31
Preoperative risk score 0.75
 Low risk, 0–3 points 87 78 90 6 7 3 3
 Intermediate risk, 4 points 129 90 70 23 18 16 12
 High risk, 5–6 points 231 119 52 65 28 47 20
 Very high risk, ≥7 points 119 22 18 57 48 47 20

Numbers present the number of patients with resected, distant metastatic, and locally advanced disease. The percentages represent the positive predictive values of the subgroups of predictor variables and staging systems. The C-index describes the discriminative performance of the respective variables.

*

Bismuth classification describes the extent of bile duct involvement.

Numbers do not sum to group totals because three patients could not be classified for the Blumgart T-staging.

LN, lymph nodes; PV, portal vein; HA, hepatic artery.