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. 2018 Aug 8;8(8):e020665. doi: 10.1136/bmjopen-2017-020665

Table 5.

Age-adjusted and sex-adjusted ORs and 95% CIs for IR, MS and its components according to haemoglobin A1c categories

ADA criteria P for trend Our proposed criteria P for trend
<5.7% 5.7%–6.5% ≥6.5% <5.5% 5.5%–6.1% ≥6.1%
Elevated BP 1 (ref) 1.55
(0.88 to 2.74)
17.75**
(3.26 to 96.76)
0.002 1 (ref) 1.37
(0.89 to 2.15)
5.63**
(1.88 to 16.65)
0.006
Dyslipidaemia 1 1.53
(0.91 to 2.57)
5.02*
(1.22 to 20.61)
0.026 1 1.61*
(1.10 to 2.37)
3.34*
(1.17 to 9.54)
0.008
IR 1 2.10**
(1.25to 3.55)
21.50**
(2.56 to 180.56)
<0.001 1 2.19**
(1.46 to 3.29)
8.69*
(2.54 to 29.70)
<0.001
MS 1 1.95*
(1.04 to 3.64)
20.80**
(4.15 to 104.22)
<0.001 1 2.09**
(1.27 to 3.45)
11.63**
(3.85 to 35.10)
<0.001

*Versus ref. p<0.05; **versus ref. p<0.01.

ADA, American Diabetes Association; BP, blood pressure; IR, insulin resistance, defined by the index of homeostasis model assessment of insulin resistance >2.6; MS, metabolic syndrome.