Table 2.

ALIC⁴E schedule of procedures

	Screening	Baseline day 1	Day 1–14	Day 14–28	Post day 28
Eligibility assessment*	✓
Informed consent*†		✓
Baseline CRF*		✓
Physical examination*		✓
Swab(s)*		✓
Randomisation*		✓
Dispensing of trial drugs*		✓
Symptom diary†			✓
Day 2–4 phone call‡			✓
Day 14–28 phone call‡				✓
After day 28 phone call‡					✓
Clinical notes review§‡					✓
Adverse event assessments‡			✓		✓
SAE follow-up‡			✓		✓

*Completed by recruiter.

†Completed by participant, includes standardised written health-related quality of life assessment and documents resource use.

‡Completed by trial team (Chief Investigator/Principal Investigator/coordinator), day 28 call includes standardised verbal health-related quality of life assessment.

§Country dependent.

ALIC⁴E, Antivirals for influenza-Like Illness? An rCt of Clinical and Cost effectiveness in primary CarE; CRF, case report form; SAE, serious adverse event.