Table 3B.
Risk factors for study outcomes, multivariable estimates (GA at enrolment >20 weeks)
| Characteristics | Study outcomes | ||||
| Caesarean sections n=4816, 20% RR (95% CI)† |
Pregnancy-related maternal complications n=3260, 14% RR (95% CI)† |
Stillbirths n=488, 2% RR (95% CI)† |
Neonatal deaths (within 28 days of birth) n=390, 1% RR (95% CI)† |
Low birth weight (<2500 g) n=3776, 16% RR (95% CI)† |
|
| Mother’s age (years) | |||||
| <20 | 0.63 *(0.46–0.86) | 0.78 (0.58 to 1.07) | 1.28 (0.66 to 2.49) | 1.47 (0.75 to 2.87) | 1.17 (0.92 to 1.48) |
| 20–29 | Ref | Ref | Ref | Ref | Ref |
| >29 | 1.66** (1.48 to 1.86) | 1.37** (1.18 to 1.60) | 2.31** (1.70 to 3.13) | 1.47 (1.00 to 2.16) | 1.29** (1.13 to 1.48) |
| Mother’s education (grades) | |||||
| Primary or less (≤4) | 0.45** (0.40 to 0.50) | 0.61** (0.54 to 0.68) | 1.51* (1.14 to 2.01) | 1.56* (1.13 to 2.14) | 1.08 (0.98 to 1.19) |
| Secondary (5–10) | 0.66** (0.62 to 0.71) | 0.87** (0.80 to 0.94) | 1.34* (1.05 to 1.71) | 1.37* (1.04 to 1.80) | 1.10* (1.02 to 1.19) |
| University (>10) | Ref | Ref | Ref | Ref | Ref |
| Parity | |||||
| Nulliparous | 1.51** (1.41 to 1.60) | 1.98** (1.83 to 2.15) | 1.25* (1.04 to 1.51) | 1.31* (1.06 to 1.61) | 1.31** (1.23 to 1.40) |
| 1–2 | Ref | Ref | Ref | Ref | Ref |
| >2 | 0.42** (0.32 to 0.55) | 0.74* (0.56 to 0.98) | 0.89 (0.56 to 1.42) | 1.49 (0.95 to 2.34) | 1 (0.84 to 1.20) |
| Anaemia (g/dL) | |||||
| Severe/moderate (<10) | 0.79** (0.72 to 0.87) | 0.87* (0.78–0.97) | 2.35** (1.56 to 3.53) | 2.76** (1.73 to 4.42) | 1.33** (1.19 to 1.49) |
| Mild (10–11) | 0.87** (0.80 to 0.94) | 0.87* (0.78 to 0.97) | 1.81* (1.20 to 2.72) | 1.73* (1.08 to 2.76) | 1.07 (0.96 to 1.20) |
| Normal (≥11) | Ref | Ref | Ref | Ref | Ref |
| Body mass index (kg/m2) | |||||
| Underweight (<18.5) | 0.84** (0.77 to 0.91) | 0.82** (0.74 to 0.90) | 1.12 (0.91 to 1.39) | 1.12 (0.88 to 1.42) | 1.28** (1.19 to 1.38) |
| Normal (18.5 to 24.9) | Ref | Ref | Ref | Ref | Ref |
| Overweight or obese (≥25) | 1.59** (1.45 to 1.74) | 1.55** (1.38 to 1.73) | 0.7 (0.44 to 1.10) | 1.03 (0.67 to 1.60) | 0.78* (0.68 to 0.91) |
*P<0.05, **p<0.001.
†Obtained by multivariable GEE regression models for each outcome, separately.
GA, gestational age; GEE, generalised estimating equations.