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. 2018 Aug 8;8(8):e021623. doi: 10.1136/bmjopen-2018-021623

Table 3B.

Risk factors for study outcomes, multivariable estimates (GA at enrolment >20 weeks)

Characteristics Study outcomes
Caesarean sections
n=4816, 20%
RR (95% CI)†
Pregnancy-related
maternal complications
n=3260, 14%
RR (95% CI)†
Stillbirths
n=488, 2%
RR (95% CI)†
Neonatal deaths
(within 28 days of birth)
n=390, 1%
RR (95% CI)†
Low birth weight
(<2500 g)
n=3776, 16%
RR (95% CI)†
Mother’s age (years)
 <20 0.63 *(0.46–0.86) 0.78 (0.58 to 1.07) 1.28 (0.66 to 2.49) 1.47 (0.75 to 2.87) 1.17 (0.92 to 1.48)
 20–29 Ref Ref Ref Ref Ref
 >29 1.66** (1.48 to 1.86) 1.37** (1.18 to 1.60) 2.31** (1.70 to 3.13) 1.47 (1.00 to 2.16) 1.29** (1.13 to 1.48)
Mother’s education (grades)
 Primary or less (≤4) 0.45** (0.40 to 0.50) 0.61** (0.54 to 0.68) 1.51* (1.14 to 2.01) 1.56* (1.13 to 2.14) 1.08 (0.98 to 1.19)
 Secondary (5–10) 0.66** (0.62 to 0.71) 0.87** (0.80 to 0.94) 1.34* (1.05 to 1.71) 1.37* (1.04 to 1.80) 1.10* (1.02 to 1.19)
 University (>10) Ref Ref Ref Ref Ref
Parity
 Nulliparous 1.51** (1.41 to 1.60) 1.98** (1.83 to 2.15) 1.25* (1.04 to 1.51) 1.31* (1.06 to 1.61) 1.31** (1.23 to 1.40)
 1–2 Ref Ref Ref Ref Ref
 >2 0.42** (0.32 to 0.55) 0.74* (0.56 to 0.98) 0.89 (0.56 to 1.42) 1.49 (0.95 to 2.34) 1 (0.84 to 1.20)
Anaemia (g/dL)
 Severe/moderate (<10) 0.79** (0.72 to 0.87) 0.87* (0.78–0.97) 2.35** (1.56 to 3.53) 2.76** (1.73 to 4.42) 1.33** (1.19 to 1.49)
 Mild (10–11) 0.87** (0.80 to 0.94) 0.87* (0.78 to 0.97) 1.81* (1.20 to 2.72) 1.73* (1.08 to 2.76) 1.07 (0.96 to 1.20)
 Normal (≥11) Ref Ref Ref Ref Ref
Body mass index (kg/m2)
 Underweight (<18.5) 0.84** (0.77 to 0.91) 0.82** (0.74 to 0.90) 1.12 (0.91 to 1.39) 1.12 (0.88 to 1.42) 1.28** (1.19 to 1.38)
 Normal (18.5 to 24.9) Ref Ref Ref Ref Ref
 Overweight or obese (≥25) 1.59** (1.45 to 1.74) 1.55** (1.38 to 1.73) 0.7 (0.44 to 1.10) 1.03 (0.67 to 1.60) 0.78* (0.68 to 0.91)

*P<0.05, **p<0.001.

†Obtained by multivariable GEE regression models for each outcome, separately.

GA, gestational age; GEE, generalised estimating equations.