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| MICa (μM) |
|||||
|---|---|---|---|---|---|
| ID | WTb | T313Ic | fold shift | M342Td | fold shift |
| 1 | 1.3 | 53 | 41 | 25 | 19 |
| 21 | 0.08 | >20 | >250 | 4.8 | 60 |
| 35 | 5.8 | >50 | >8.6 | >20 | >3 |
| 37 | 0.24 | 11 | 46 | ND | ND |
| 39 | 0.53 | 59 | 110 | 7 | 14 |
Minimum inhibitory concentration (MIC90) is the minimum concentration required to inhibit the growth of M. tuberculosis in liquid culture.
Wild-type strain.
QcrB T313I mutant strain.
QcrB M342T mutant strain. ND Not Done
