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. Author manuscript; available in PMC: 2018 Aug 13.
Published in final edited form as: Clin Pediatr (Phila). 2011 Feb 11;50(6):535–542. doi: 10.1177/0009922810394838

Table 2.

Bacteriological Treatment Success by Country

Treatment Group
Treatment Differencea
Adjusted Treatment
Differenceb
Country Amoxicillin Success
Percentage (n/Total)
IM BPG Success
Percentage (n/Total)
Percentage
Difference
95% CI Percentage
Difference
95% CI

Intention to treat analysis
 Croatia (n = 121) 70.3 (45/64) 66.7 (38/57)  3.6 −12.9, 20.2   2.5 −13.8, 18.9
 Egypt (n = 247)  61.8 (76/123)  75.8 (94/124) −14.0c −25.5, −2.59 −15.1c −26.6, −3.4
Per protocol analysis
 Croatia (n = 111) 68.5 (37/54) 66.7 (38/57)  1.8 −15.6, 19.3   1.1 −16.2, 18.5
 Egypt (n = 161) 67.6 (25/37)  75.8 (94/124)  −8.2 −25.1, 8.6  −9.3 −26.3, 7.8

Abbreviations: IM BPG, intramuscular benzathine penicillin G; 95% CI, 95% confidence interval.

a

Difference in percentage success rates (amoxicillin – IM BPG).

b

Adjusted analysis: intention to treat, controlled for age and gender; per protocol, controlled for compliance, age, and gender (amoxicillin – IM BPG).

c

Statistically significant: treatment difference P = .016; adjusted treatment difference P = .011.