Table 2.
Treatment Group |
Treatment Differencea |
Adjusted Treatment Differenceb |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Country | Amoxicillin Success Percentage (n/Total) |
IM BPG Success Percentage (n/Total) |
Percentage Difference |
95% CI | Percentage Difference |
95% CI | |||||
Intention to treat analysis | |||||||||||
Croatia (n = 121) | 70.3 (45/64) | 66.7 (38/57) | 3.6 | −12.9, 20.2 | 2.5 | −13.8, 18.9 | |||||
Egypt (n = 247) | 61.8 (76/123) | 75.8 (94/124) | −14.0c | −25.5, −2.59 | −15.1c | −26.6, −3.4 | |||||
Per protocol analysis | |||||||||||
Croatia (n = 111) | 68.5 (37/54) | 66.7 (38/57) | 1.8 | −15.6, 19.3 | 1.1 | −16.2, 18.5 | |||||
Egypt (n = 161) | 67.6 (25/37) | 75.8 (94/124) | −8.2 | −25.1, 8.6 | −9.3 | −26.3, 7.8 | |||||
Abbreviations: IM BPG, intramuscular benzathine penicillin G; 95% CI, 95% confidence interval.
Difference in percentage success rates (amoxicillin – IM BPG).
Adjusted analysis: intention to treat, controlled for age and gender; per protocol, controlled for compliance, age, and gender (amoxicillin – IM BPG).
Statistically significant: treatment difference P = .016; adjusted treatment difference P = .011.